Dermoscopic patterns of basal cell carcinoma (BCC) are well defined, but the dynamics of dermoscopic changes in time were\r\napparently never described so far. In this paper, prominent changes were observed over a 8-week period, allowing to establish a\r\nclose connection between spoke wheel areas and maple leaf-like aspects, through progressive thickening of the former ones. A\r\nchronobiological phenomenon ruling synchronous apoptosis in some of the most superficial BCC nests is suggested, leading to a\r\nwax and wane process of millimetric crusts, taking part in the spontaneous BCC regression/progression process.
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